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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd139f1a9f6cfdff2b29d9f246f31357afb2e09d3f4bc6ae11bf446730cba4bf3' 
  AND token = 'qX2ZvQ3bI35SIMBqf/z9UKz61BHABzhGBHERynwQfAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}