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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ad8f8f1c917a3b76ba274a756ff0783992021635a7bbb753ce7c7614722672' 
  AND token = 'rvEolgkwTtuugKGg8PMbCOzgjx7WeIbPcm3leRBZYao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}