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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6670af59a944a010027491f0bb994bc0f37e35ceba8b377f532ddf35cd01010' 
  AND token = 'ktizv1dL69f+kejOJmV7HJeIlDQnCdmBqqQgi8dZgzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}