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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3791ae94671d30f56c6a79b59b026d04b05c102a1d2a0b5fca7df3526261982' 
  AND token = 'QuaTPBGMTc6zHbDkboh3cbWDHGMlFONxF6Mv8mQUoCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}