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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e416034d0027ab0a0d308c258aa097aefc74b704f34a7b1cde3c43323cce8ff9' 
  AND token = 'YV9bvKWCol3/+kxnLrmBYNKnnDuCjcuDJaZ4G52gEpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}