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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72beabcf9a33c8159c512b4410bc83b2697c9ccd12ad71ec802f6b72d0829f0f' 
  AND token = 'HbQ+M8F2YcZDDTXhAnHixI2EnyZZPfkE+SgidGsaIIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}