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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95080f3b9f3421bd2f8cc00781e36f68fedfe1a83dce803cc585dd0049f321b' 
  AND token = 'm9WwxsKNQK1qrlZoFnf38DqbeBON+cnVRUGNWj85vaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}