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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ad57c387f8f08a086848915c160e22190919c55f933e3e35a99b2892780b0d' 
  AND token = 'kymaerYWo5WgBGk3gd+z598HMP/dtd2Jh6OZZI+4fyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}