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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4820738a2682ad82537f6b61aa0f9c25852df6622480ea8f546af06616dd97db' 
  AND token = 'zrq/qi69ut0h+RknWH8FPOOrIL0+DYLn9LK26pZGCb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}