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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc0463133a53e27cd2f6dea5f1b7967405305bfdeead20ecda770d1881a08f4' 
  AND token = 'GIpr68gFsXIYcxFott7EfNVDRcMd0CN99SUyD5iJue4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}