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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5fa880fd3234235074302a7b968298e3709fd012018fe7df381893c4b4d1996' 
  AND token = '1a1Yaw4aCGv9GbGMl1D1DcAy0pfjyWs57CtcY1RaT+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}