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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718bf7709c800809746dfe96271818e1c24a922f62121b5d0e891978227b8d79' 
  AND token = '8giyjQ7rhZaid4qJSFVYLmD4QM9cOlGhogG3jQQueiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}