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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b31fd743cab22b414d4e657a7d93a9fd67f03d0bcaf309898585eaccb5da1821' 
  AND token = 'j2I0TUjh9D+549VW1Jp8XyOutFLVToT0w7bKT2de58c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}