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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c685e26344f9c209cdc13de5dc4a33b7c83216c0a69d5504936cfe7f526a588' 
  AND token = 'ZU9l3GrR2Eukm/2ylixs5PaaG62Ey9wpxMKSRN4IBU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}