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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0491db0ae64f62f0985a3aadd42796b8e81217702b6374e47dee958ee617b424' 
  AND token = '2ofCC2ZWBwb5rHqA+NtNHIDWYCOMHNyYrZcup9zVdbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}