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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c648ee9b2e69afeb7e674fb967e0a45f2a0412442058a11aacb5c5fd4928b11' 
  AND token = 'GWjF0tIwTN+wOfD7UV8mI5Ro955OKsQ1M1zPz9lxZo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}