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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc39bd46c386f3fe6a4bfdb44a064c918dc50520567dcbe43c45fdb672f90104' 
  AND token = 'XIsnLpQonMwhn8O2AjHwR3jbE2cglcYZFp4vgcV6AUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}