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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc75b64b32e1a17f03b5e8d8c375673cdf74a0d93037b98ba406da15718d1992' 
  AND token = 'XY+e8PQrmLMOx+GA429ODu/qRMXI9D33buBWs7ucu04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}