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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df444ca1f72e3ba1aacb7ca701f28546e0f78d1f9936a25c502e1b5e2aaff5ec' 
  AND token = 'cwdIQL9an5rJPLQS0velDway3FHycMVTJXwbdBxaB8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}