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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d592646d8dc5674a194a572014b840c209f99b693d598d4b7bbba5c7e6e523' 
  AND token = 'hd6r9VJnCo0n/hUMfMR7wNIA7A1yEjQY1afT/9G5qGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}