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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c691dcf0f60157979e1e078a1a64f2280ea6763ecaa3e1967b4c9be451edcecf' 
  AND token = 'LCmlyU7ke3rchWNfGPSM9qjRJ2FvE+AzH04cQ0OkVNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}