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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e50d82bf3130cbacb963ccb5ead53f9d16256943f0c8da8005a8c37f15a2cb4' 
  AND token = 'UQfzzwJoPnRaUL2zMRYtvzSUC+/iKL8eZRDc1NPyjAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}