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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c282906fb6b9564f947103737c8d42ab47d50256807a8e9bef2443c4de336df' 
  AND token = 'bZ7g5FIdM3M2GBw90xBxUrObgxd1GB61uQszi+d+vFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}