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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f07d947d8ce49d2502e65332e59428bbb6c3a3e1f062a6d4f3a04b3f057d9e97' 
  AND token = 'z86W6aI1H2+WJZJDAQ//ha3p2uEOxhN91uwCKZ64Vj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}