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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6493f03f8eca1d21a00cc8924469a0c31f8473b2b1dac5ddba7935f1132c7478' 
  AND token = 'FxRf76MUN8S3Z9GqeXYe/JkH26AHOlC0NEvCiNFyrjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}