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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e102420f73fbb46a971f67603eefd247c7e22cd60e9d8a4850f24423a67767' 
  AND token = 'T1H4CpjYyi4zdH6ElPDZwQG0qkUFspdc21V6bpCxRu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}