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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7922aa75b1870f5091a5a325c412d48aae466498b0cc1d3052fd6ffbc0efe3' 
  AND token = 'vSss0SXaOOtaoppTtnUfgzO/diBlifXhHnopU4DDPXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}