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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6022000a4cdb9e35ba4fbb4979b13975e96f0fa6e9239888c7a637bfb9a443e4' 
  AND token = '+XT0xSINDMTaF8g0wQKhYLEnjYNKLEZxnPlCtWA+LUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}