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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bf6772b078e38051892cc3f2b59cb7ed92817f17f83e4212d7a227906c4cc1' 
  AND token = 'DB5JDqyPZPeYDNg6uM2Lx9SwbAx9SVGg2D1+wytZUJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}