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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5468edda1fba804f7252fa080fd7179aad4453bc5508c40fffb0694aab5246' 
  AND token = 'I7TIO9ne9RgHbh4rcTjJgbPPxxj2k6xJgxN9YErB6Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}