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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9854a6e381781c857001b8881214a3ea746c8a094866bc93b46d80c9ecd3bcac' 
  AND token = 't5JinmMBb1G8ZnVpdwX5CbC4Xre9GU/8xcwAbPti+7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}