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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d58b65c1c74095a8bdc80e7883b4d491e8ee22087cd35a261b1cbc37d845012' 
  AND token = '69+9G7T3OyZrBu3QL33kDCVVJ88u1eKgJXcO7JtEjCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}