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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02a6c375e3e744e647b460a0e52bcc25c78f3186d4569a8062270672dca5d84' 
  AND token = 'ATWDLN8MII+PBmRXlEDl892/ZT21eTCMg/lQI8aK5tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}