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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '704df4c1c80da604edad221fc6af28cf0ea7cf9289f0bb0dda2e512037854cb0' 
  AND token = 'Ym1X6X8uC60BqmPXq5lHq/9LNP7E72LV4BaqzO/Od9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}