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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc6a49a5df9494b75507051803455467c254e306b60eef89be3326af351398f' 
  AND token = 'WUC4akr2oZk18h3L5OMg6a8CWenNXXlW7wrxh+zXHWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}