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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52c2cc7ddb420f7160315a823dd187653c866efce95279ff8dca7a45508d5c6' 
  AND token = '+yaBD9tmXFO7CzaGouxGMIiyAdeudp/HOVU+ZOtSezU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}