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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa35d53c26ee9de6ae197c79bc378eaff9104dfac3f5485d407c35eb2605991' 
  AND token = 'lbt/64POYrziTzJUh8L1ACT/h1zhUXECnFn/ht8BNiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}