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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca382e50a77d616e9d273a6fba07373e34c028c4503dcc7d350d9f1d43a03d5e' 
  AND token = 'Oj+OgOTVWTAE/S8yfO3NeJBxc55Q6I8+YOOODhfHXqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}