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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3d29c6a9af2d33e65c4669a652f4466353ecfc355d9e516e9b250c5e144d0f6' 
  AND token = '9yCEDWDP3l516B1dzWA9D0EY5x5Ipt+GP8HJ9oH4oUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}