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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0110efe48232695ee4d8cad98075ea59d71d8fc3f56d53b0551f29ea5b265711' 
  AND token = '/qfHDKnyIfgkCDgBu1REv0I1as1Aci4MAZ+WS/Uce6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}