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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c1257e052e870592631170242fde41cd4c18d12d868b0a30f8402cd7514da0' 
  AND token = 'we8hPw6iehFvNC/MQRxx7FB3Sk6u48z2bIcV4IqQp1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}