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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461b655a653793adbd1442ef917a03df653e00eed5559ebeb060eb2f8c20f125' 
  AND token = 'RcMDIGZwrXUNvmFj2kc42Df3mYAVrHxHzjulR8eaXXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}