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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e16573253e235e889093b2ac9e933c4c194d688873a0aeea786594feaa65ca' 
  AND token = '6Iw+eev6XncYw/UjQOyLP6HoI5OmfsKKKYiaqBvk/x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}