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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2433b836dc5eecaf1a351c64e3b78823eb542eb5b31ab3302317b1b3f304c02b' 
  AND token = 'KI0DhDKYg9/CKfz42OvHGNnkXLff1YWW85zXvMjihKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}