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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6144acac980bcb86cff57cae9b3774fef9202c4476c3e8692557f450e110596c' 
  AND token = 'fT1KAehqMYDCz8HufAXisrOBni1UWbXXZkOrnX0hEzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}