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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ddc59d548cf9a496edcc264ec38c0bb7a0c13538ba48955ccf1a62130584f60' 
  AND token = 'P5j39ut7hpBbooGpOYyBC+2eLJh0dNni7Bcdf20NoRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}