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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917e39011ee4bdf38ad30e51c553766df90c52e7bdada3b3f1496bbdcd358044' 
  AND token = '8Cv0dO/u4FPqIoRMmT6CyzNHosGKZitXXjv8TkT8epY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}