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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b9110f30a6e0e7a93d7c3e2a903b7f1e4871d4c29774358fac6f38e6649ed51' 
  AND token = 'ssdmEtE4hDxtsTunceEm3fAckCrJb1qPuUYoZsis1N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}