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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8363cc974ac3fd905548b0bed390250b3a3e9c7fc25d45a5a405cb41caab9360' 
  AND token = 'V4Sl420G+edTadI1OLI4DzvP/fd3cOSno734KpAdRJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}