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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd989b03b1c4b65bdf132375d252e9bc12564f42e6f901b8cfce303009896cf' 
  AND token = 'JCYOzq3BcxOzEXyV3ysHVaHNdoHIplxDxJJ/2UT2FzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}